Intensive Care Medicine OnlineFirst articles

16.05.2024 | Editorial

Treating necrotizing skin and soft-tissue infections

Typical cases are usually readily identified on clinical grounds, leading to early emergency admission and source control. In contrast, underestimation of the burden of comorbidities, slow onset or atypical symptoms without sepsis, are common risk …

verfasst von:: Philippe Montravers, Anna Norrby-Teglund, Patricia Munoz

16.05.2024 | Letter

Volatile sedation practices in patients with severe acute respiratory distress syndrome under VV-ECMO support

verfasst von:: Sara Alcántara Carmona, Ana del Saz, Sofía Contreras, Jordi Riera, Aaron Blandino, the Volatile Sedation on VV-ECMO Research Group

15.05.2024 | Systematic Review

Interventions for improving critical care in low- and middle-income countries: a systematic review

Quality improvement (QI) interventions aim to systematically change a predefined process or pathway of patient care, and often target timeliness, efficiency, effectiveness, equity, and safety of care delivery [ 1 ]. Intervention strategies …

verfasst von:: Duncan Wagstaff, Sumaiya Arfin, Alba Korver, Patrick Chappel, Aasiyah Rashan, Rashan Haniffa, Abi Beane

Open Access 15.05.2024 | Original

Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study

As the population ages, a greater number of persons are living with functional limitation and frailty [ 1 ]. Frailty is a state of increased vulnerability resulting from a decline in reserve across multiple physiological systems, increasing …

verfasst von:: John Muscedere, Sean M. Bagshaw, Michelle Kho, Sangeeta Mehta, Deborah J. Cook, J. Gordon Boyd, Stephanie Sibley, Han T. Wang, Patrick M. Archambault, Martin Albert, Oleksa G. Rewa, Ian Ball, Patrick A. Norman, Andrew G. Day, Miranda Hunt, Osama Loubani, Tina Mele, Aimee J. Sarti, Jason Shahin, the Canadian Critical Care Trials Group

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15.05.2024 | Editorial

Using echocardiography to predict fluid-responsiveness and manage the need for fluids

1 The right ventricle (RV) is severely dilated (the right ventricle is bigger than the left ventricle (LV)), with or without a paradoxical septal motion [ 7 ]. Giving more fluids could be deleterious even in the case of non-severe right ventricular …

verfasst von:: Antoine Vieillard-Baron, Florence Boissier, Michel Slama

Open Access 15.05.2024 | Narrative Review

Management of hematological patients requiring emergency chemotherapy in the intensive care unit

Hematological malignancies may require rapid-onset treatment because of their short doubling time, notably observed in acute leukemias and specific high-grade lymphomas. Furthermore, in targeted onco-hematological scenarios, chemotherapy is deemed …

verfasst von:: Antoine Lafarge, Dara Chean, Livia Whiting, Raphaël Clere-Jehl, the Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologie (Grrr-OH) Network, and the Clinical Research in Intensive Care, Sepsis (CRICS) Group

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15.05.2024 | Letter

Successful implementation of the Spanish model of organ donation in a Brazilian state

verfasst von:: Joel de Andrade, Beatriz Dominguez-Gil, Elisabeth Coll, Glauco Adrieno Westphal

Open Access 13.05.2024 | Editorial

Finding the optimal tidal volume in acute respiratory distress syndrome

The ARDS Network study was the seminal study introducing the concept of protective mechanical ventilation. However, a fixed V _Tcut-off (6 ml/kg PBW) has been recently questioned [ 9 – 11 ]. New evidence suggests that it may be more advantageous to …

verfasst von:: Mariangela Pellegrini, Lorenzo Del Sorbo, V. Marco Ranieri

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Open Access 13.05.2024 | Original

Oral challenge vs routine care to assess low-risk penicillin allergy in critically ill hospital patients (ORACLE): a pilot safety and feasibility randomised controlled trial

Penicillin allergy labels (patient reported penicillin allergies) are present in up to 15% of adult hospital patients [ 1 , 2 ] and in 6.8% of critically ill patients in the intensive care unit (ICU) [ 3 ]. The prevalence of penicillin allergy …

verfasst von:: Morgan T. Rose, Natasha E. Holmes, Glenn M. Eastwood, Sara Vogrin, Fiona James, Joseph F. De Luca, Rinaldo Bellomo, Stephen J. Warrillow, Michelle Phung, Sara L. Barnes, Brendan Murfin, Ben Rogers, Belinda Lambros, Brennan Collis, Trisha N. Peel, Monica A. Slavin, Jason A. Trubiano

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13.05.2024 | Editorial

When is the optimal time to stop continuous renal replacement therapy in children?

verfasst von:: Shaegan Irusen, Antoine Schneider, Michael Joannidis

13.05.2024 | Editorial

Empirical antimicrobials in the intensive care unit

verfasst von:: Liesbet De Bus, Kostoula Arvaniti, Fredrik Sjövall

13.05.2024 | Understanding the Disease

Ten tips on sepsis-induced thrombocytopenia

A platelet count is the number of platelets per volume, typically analysed by automated instruments. In cases of abnormal counts, counts are repeated manually. Reported platelet counts are strictly quantitative and qualitative platelet dysfunction …

verfasst von:: Marc Leone, Nathan D. Nielsen, Lene Russell

08.05.2024 | Letter

Failure of target attainment for beta-lactam antibiotics and ciprofloxacin in acute brain-injured intensive care patients

verfasst von:: Saliha Ergezen, Tim M. J. Ewoldt, Mathieu van der Jagt, Birgit C. P. Koch, Henrik Endeman, the DOLPHIN Investigators

07.05.2024 | Correspondence

Ex ante reflection will not grant immunity to moral troubles among clinicians at organ donation in the ICU

verfasst von:: Anna-Henrikje Seidlein, Jos M. Latour, Julie Benbenishty

07.05.2024 | Correspondence

Intensive Care admission aiming at organ donation as a duty of the intensivist: every organ, every time

verfasst von:: Rui Paulo Moreno, João Paulo Almeida e Sousa, Ricardo Godinho de Matos, Eduardo Sousa

07.05.2024 | Correspondence

Post-intensive care unit follow-up: don’t stop it now!

verfasst von:: Anne-Françoise Rousseau, Pauline Minguet, Sarah Neis-Gilson, Benoit Misset, Bernard Lambermont

07.05.2024 | Correspondence

Are post-intensive care unit consultations actually harmful?

verfasst von:: José Manuel Añón, Carola Giménez-Esparza, Kapil Nanwani-Nanwani, María Rosario Úrbez, María Victoria Bonan

Open Access 06.05.2024 | Editorial

Definitions, guidelines and opinions: the white, the black and the grey

verfasst von:: Luciano Gattinoni

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06.05.2024 | Editorial

Acute respiratory distress syndrome guidelines: oceans apart or rivers that merge?

In this article, the first of a two-part commentary, we will compare and contrast potential sources of disagreement between the ATS and ESICM guidelines. Our primary aim is to comment on how evidence was evaluated and the rationale behind the …

verfasst von:: Luigi Camporota, Carolyn S. Calfee, Giacomo Grasselli

06.05.2024 | Editorial

Mind the gap: understanding the discordance between the ATS and ESICM ARDS guidelines—the ATS perspective

verfasst von:: Sarina K. Sahetya, Bram Rochwerg, Eddy Fan

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin