Anzeige
Erschienen in:
05.06.2023 | Original Article
Comparison of phase contrast magnetic resonance imaging and scintigraphy for determination of split pulmonary blood flow in children and young adults with congenital heart disease
Erschienen in: Pediatric Radiology | Ausgabe 10/2023
Einloggen, um Zugang zu erhaltenAbstract
Background
Measurement of differential blood flow to the lungs is important to understanding flow dynamics in the setting of congenital heart disease. Split blood flow via the pulmonary arteries guides and demonstrates the effect of interventions. Minimally invasive imaging of pulmonary blood flow can be achieved with scintigraphy or magnetic resonance imaging (MRI).
Objective
To assess agreement of pulmonary blood flow measurements obtained by scintigraphy and MRI in children and young adults.
Materials and methods
We performed a retrospective review of patients < 21 years of age who had undergone both nuclear medicine pulmonary perfusion scans (Tc-99 m MAA) and cardiac MRI examinations from January 2012 to August 2021 at our tertiary pediatric hospital. Patient demographics, medical/surgical information, and estimates of split blood flow by both modalities were recorded. Pearson’s correlation coefficient was used to determine the relationship between split blood flow measured by the two examinations. Agreement was calculated using interclass correlation coefficient (ICC) for absolute agreement and Bland–Altman difference analysis.
Results
Correlation between split blood flow measured by scintigraphy and MRI using net flow was 0.90 (95% CI: 0.83–0.94, P < 0.001) and the ICC for agreement on split blood flow was 0.90 (95% CI: 0.84–0.94). Mean difference in split blood flow by Bland–Altman analysis was 0.79% with 95% limits of agreement (-11.2 to 12.8%).
Conclusion
There is excellent agreement between Tc-99 m scintigraphy and phase contrast MRI for quantification of split pulmonary blood flow in children and young adults with congenital heart disease.
Graphical Abstract
×
![]()