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Erschienen in: European Spine Journal 11/2023

03.09.2023 | Original Article

Vertebral bone quality score for opportunistic osteoporosis screening: a correlation and optimal threshold analysis

verfasst von: Emre Özmen, Ozancan Biçer, Emre Meriç, Esra Circi, Alican Barış, Serdar Yüksel

Erschienen in: European Spine Journal | Ausgabe 11/2023

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Abstract

Purpose

This study investigated the vertebral bone quality (VBQ) score as a potential tool for opportunistic osteoporosis screening and its correlation with dual-energy X-ray absorptiometry (DXA) values.

Methods

In a single-center retrospective cohort of 130 patients, VBQ and DXA measures were compared using various statistical analyses. The optimal VBQ threshold for predicting osteoporosis was determined using receiver operating characteristic (ROC) analysis.

Results

VBQ exhibited a significant negative association with DXA values, suggesting that higher VBQ scores are indicative of lower bone density. Age and VBQ were significant predictors of osteoporosis, with both increasing the log-odds of the condition. An optimal VBQ threshold of 2.7 was determined, demonstrating fair discriminatory power and high negative predictive value.

Conclusion

The study highlighted the potential of VBQ as a diagnostic tool for osteoporosis with high intra- and inter-observer reliability. The optimal VBQ threshold of 2.7 can aid in ruling out osteoporosis and identifying individuals for further evaluation.
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Metadaten
Titel
Vertebral bone quality score for opportunistic osteoporosis screening: a correlation and optimal threshold analysis
verfasst von
Emre Özmen
Ozancan Biçer
Emre Meriç
Esra Circi
Alican Barış
Serdar Yüksel
Publikationsdatum
03.09.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
European Spine Journal / Ausgabe 11/2023
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-023-07912-0

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