Skip to main content

2023 | OriginalPaper | Buchkapitel

26. Training von Patienten mit linksventrikulären mechanischen Herzunterstützungssystemen und nach Herztransplantation

verfasst von : Christiane Marko, Francesco Moscato, Rochus Pokan

Erschienen in: Sportkardiologie

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Patienten nach LVAD-Implantation benötigen eine intensive interdisziplinäre Betreuung und Überwachung zur Vermeidung und Behandlung von Device-spezifischen Komplikationen. Die wissenschaftliche Evidenz ist nicht ausreichend, um Guidelines für das Training von LVAD-Patienten zu erstellen, jedoch sprechen die vorhandenen Daten dafür, dass es mit Steuerung der Intensität nach der BORG-Skala, wie auch bei Patienten nach Herztransplantation, sicher und erfolgreich durchgeführt werden kann. In Zukunft muss geklärt werden, warum es bei manchen Patienten im Langzeitverlauf zu keiner Verbesserung der Leistungsfähigkeit kommt. Bei entsprechenden Umfängen und Intensitäten sind, vergleichbar mit gesunden Athleten, auch transplantierte Herzen trainierbar. Der Schwerpunkt des rehabilitativen Trainings nach einer Herztransplantation liegt aber eindeutig in der Adaptation der Skelettmuskulatur.
Literatur
1.
Zurück zum Zitat Molina EJ, Shah P, Kiernan MS et al (2021) The society of thoracic surgeons intermacs 2020 annual report. Ann Thorac Surg 111(3):778–792PubMed Molina EJ, Shah P, Kiernan MS et al (2021) The society of thoracic surgeons intermacs 2020 annual report. Ann Thorac Surg 111(3):778–792PubMed
2.
Zurück zum Zitat Kormos RL, Cowger J, Pagani FD et al (2019) The Society of Thoracic Surgeons Intermacs database annual report: Evolving indications, outcomes, and scientific partnerships. J Heart Lung Transplant 38(2):114–126PubMed Kormos RL, Cowger J, Pagani FD et al (2019) The Society of Thoracic Surgeons Intermacs database annual report: Evolving indications, outcomes, and scientific partnerships. J Heart Lung Transplant 38(2):114–126PubMed
3.
Zurück zum Zitat Le Gallois JJC (1813) Experiments on the principles of life. M. Thomas, Philadelphia Le Gallois JJC (1813) Experiments on the principles of life. M. Thomas, Philadelphia
4.
Zurück zum Zitat Rose EA, Gelijns AC, Moskowitz AJ et al (2001) Randomized evaluation of mechanical assistance for the treatment of congestive heart failure (REMATCH) study group. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med 345(20):1435–1443PubMed Rose EA, Gelijns AC, Moskowitz AJ et al (2001) Randomized evaluation of mechanical assistance for the treatment of congestive heart failure (REMATCH) study group. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med 345(20):1435–1443PubMed
5.
Zurück zum Zitat McDonagh TA, Metra M, Adamo M, ESC Scientific Document Group et al 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42:3599:ehab368 McDonagh TA, Metra M, Adamo M, ESC Scientific Document Group et al 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42:3599:ehab368
6.
Zurück zum Zitat Ponikowsky P, Voors AA, Anker SD et al (2016) 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail 18(8):891–975 Ponikowsky P, Voors AA, Anker SD et al (2016) 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail 18(8):891–975
7.
Zurück zum Zitat Boyle AJ, Ascheim DD, Russo MJ et al (2011) Clinical outcomes for continuous-flow left ventricular assist device patients stratified by pre-operative INTERMACS classification. J Heart Lung Transplant 30(4):402–407PubMed Boyle AJ, Ascheim DD, Russo MJ et al (2011) Clinical outcomes for continuous-flow left ventricular assist device patients stratified by pre-operative INTERMACS classification. J Heart Lung Transplant 30(4):402–407PubMed
8.
Zurück zum Zitat Baldwin JT, Mann DL (2010) NHLBI’s program for VAD therapy for moderately advanced heart failure: the REVIVE-IT pilot trial. J Card Fail 16(11):855–858PubMedPubMedCentral Baldwin JT, Mann DL (2010) NHLBI’s program for VAD therapy for moderately advanced heart failure: the REVIVE-IT pilot trial. J Card Fail 16(11):855–858PubMedPubMedCentral
9.
Zurück zum Zitat Pagani FD, Aaronson KD, Kormos R et al (2016) The NHLBI REVIVE-IT study: understanding its discontinuation in the context of current left ventricular assist device therapy. J Heart Lung Transplant 35(11):1277–1283PubMed Pagani FD, Aaronson KD, Kormos R et al (2016) The NHLBI REVIVE-IT study: understanding its discontinuation in the context of current left ventricular assist device therapy. J Heart Lung Transplant 35(11):1277–1283PubMed
10.
Zurück zum Zitat John R, Mantz K, Eckman P, Rose A et al (2010) Aortic valve pathophysiology during left ventricular assist device support. J Heart Lung Transplant 29(12):1321–1329PubMed John R, Mantz K, Eckman P, Rose A et al (2010) Aortic valve pathophysiology during left ventricular assist device support. J Heart Lung Transplant 29(12):1321–1329PubMed
11.
Zurück zum Zitat Slaughter MS, Pagani FD, Rogers JG et al (2010) Heart- Mate II clinical investigators. Clinical management of continuous-flow left ventricular assist devices in advanced heart failure. J Heart Lung Transplant 29(4 Suppl):S1–S39PubMed Slaughter MS, Pagani FD, Rogers JG et al (2010) Heart- Mate II clinical investigators. Clinical management of continuous-flow left ventricular assist devices in advanced heart failure. J Heart Lung Transplant 29(4 Suppl):S1–S39PubMed
12.
Zurück zum Zitat Noor MR, Bowles C, Banner NR (2012) Relationship between pump speed and exercise capacity during Heart- Mate II left ventricular assist device support: influence of residual left ventricular function. Eur J Heart Fail 14(6):613–620PubMed Noor MR, Bowles C, Banner NR (2012) Relationship between pump speed and exercise capacity during Heart- Mate II left ventricular assist device support: influence of residual left ventricular function. Eur J Heart Fail 14(6):613–620PubMed
13.
Zurück zum Zitat Gross C, Marko C, Mikl J et al (2019) LVAD pump flow does not adequately increase with exercise. Artif Organs 43(3):222–228PubMed Gross C, Marko C, Mikl J et al (2019) LVAD pump flow does not adequately increase with exercise. Artif Organs 43(3):222–228PubMed
14.
Zurück zum Zitat Guglin M, Miller L (2012) Myocardial recovery with left ventricular assist devices. Curr Treat Options Cardiovasc Med 14(4):370–383PubMed Guglin M, Miller L (2012) Myocardial recovery with left ventricular assist devices. Curr Treat Options Cardiovasc Med 14(4):370–383PubMed
15.
Zurück zum Zitat Dipla K, Mattiello JA, Jeevanandam V et al (1998) Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure. Circulation 97(23):2316–2322PubMed Dipla K, Mattiello JA, Jeevanandam V et al (1998) Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure. Circulation 97(23):2316–2322PubMed
16.
Zurück zum Zitat Ogletree-Hughes ML, Stull LB, Sweet WE et al (2001) Mechanical unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in the failing human heart. Circulation 104(8):881–886PubMed Ogletree-Hughes ML, Stull LB, Sweet WE et al (2001) Mechanical unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in the failing human heart. Circulation 104(8):881–886PubMed
17.
Zurück zum Zitat Birks EJ, Tansley PD, Hardy J et al (2006) Left ventricular assist device and drug therapy for the reversal of heart failue. N Engl J Med 355(18):1873–1884PubMed Birks EJ, Tansley PD, Hardy J et al (2006) Left ventricular assist device and drug therapy for the reversal of heart failue. N Engl J Med 355(18):1873–1884PubMed
18.
Zurück zum Zitat Goldstein DJ, Naftel D, Holman W et al (2012) Continuous- flow devices and percutaneous site infections: clinical outcomes. J Heart Lung Transplant 31(11):1151–1157PubMed Goldstein DJ, Naftel D, Holman W et al (2012) Continuous- flow devices and percutaneous site infections: clinical outcomes. J Heart Lung Transplant 31(11):1151–1157PubMed
19.
Zurück zum Zitat Starling RC, Moazami N, Silvestry SC et al (2014) Unexpected abrupt increase in left ventricular assist device thrombosis. N Engl J Med 370(1):33–40PubMed Starling RC, Moazami N, Silvestry SC et al (2014) Unexpected abrupt increase in left ventricular assist device thrombosis. N Engl J Med 370(1):33–40PubMed
20.
Zurück zum Zitat Uriel N, Pak SW, Jorde UP et al (2010) Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation. J Am Coll Cardiol 56(15):1207–1213PubMed Uriel N, Pak SW, Jorde UP et al (2010) Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation. J Am Coll Cardiol 56(15):1207–1213PubMed
21.
Zurück zum Zitat Adzic A, Patel SR, Maybaum S et al (2013) Impact of adverse events on ventricular assist device outcomes. Curr Heart Fail Rep 10(1):89–100PubMed Adzic A, Patel SR, Maybaum S et al (2013) Impact of adverse events on ventricular assist device outcomes. Curr Heart Fail Rep 10(1):89–100PubMed
22.
Zurück zum Zitat Andersen M, Videbaek R, Boesgaard S et al (2009) Incidence of ventricular arrhythmias in patients on long-term support with a continuous-flow assist device (HeartMate II). J Heart Lung Transplant 28(7):733–735PubMed Andersen M, Videbaek R, Boesgaard S et al (2009) Incidence of ventricular arrhythmias in patients on long-term support with a continuous-flow assist device (HeartMate II). J Heart Lung Transplant 28(7):733–735PubMed
23.
Zurück zum Zitat Sims DB, Rosner G, Uriel N et al (2012) Twelve hours of sustained ventricular fibrillation supported by a continuous- flow left ventricular assist device. Pacing Clin Electrophysiol 35(5):e144–e148PubMed Sims DB, Rosner G, Uriel N et al (2012) Twelve hours of sustained ventricular fibrillation supported by a continuous- flow left ventricular assist device. Pacing Clin Electrophysiol 35(5):e144–e148PubMed
24.
Zurück zum Zitat Enriquez AD, Calenda B, Miller MA et al (2013) The role of implantable cardioverter-defibrillators in patients with continuous flow left ventricular assist devices. Circ Arrhythm Electrophysiol 6(4):668–674PubMed Enriquez AD, Calenda B, Miller MA et al (2013) The role of implantable cardioverter-defibrillators in patients with continuous flow left ventricular assist devices. Circ Arrhythm Electrophysiol 6(4):668–674PubMed
25.
Zurück zum Zitat Gopinathannair R, Cornwell WK, Dukes JW et al (2019) Device therapy and arrhythmia management in left ventricular assist device recipients: a scientific statement From the American Heart Association. Circulation 139(20):e967–e989 Gopinathannair R, Cornwell WK, Dukes JW et al (2019) Device therapy and arrhythmia management in left ventricular assist device recipients: a scientific statement From the American Heart Association. Circulation 139(20):e967–e989
26.
Zurück zum Zitat Vollkron M, Voitl P, Ta J et al (2007) Suction events during left ventricular support and ventricular arrhythmias. J Heart Lung Transplant 26(8):819–825PubMed Vollkron M, Voitl P, Ta J et al (2007) Suction events during left ventricular support and ventricular arrhythmias. J Heart Lung Transplant 26(8):819–825PubMed
27.
Zurück zum Zitat Potapov EV, Antonides C, Crespo-Leiro et al (2019) 2019 EACTS expert consensus on long-term mechanical circulatory support. Eur J Cardiothorac Surg 56(2):230–270PubMedPubMedCentral Potapov EV, Antonides C, Crespo-Leiro et al (2019) 2019 EACTS expert consensus on long-term mechanical circulatory support. Eur J Cardiothorac Surg 56(2):230–270PubMedPubMedCentral
28.
Zurück zum Zitat Morrone TM, Buck LA, Catanese KA et al (1996) Early progressive mobilization of patients with left ventricular assist devices is safe and optimizes recovery before heart transplantation. J Heart Lung Transplant 15(4):423–429PubMed Morrone TM, Buck LA, Catanese KA et al (1996) Early progressive mobilization of patients with left ventricular assist devices is safe and optimizes recovery before heart transplantation. J Heart Lung Transplant 15(4):423–429PubMed
29.
Zurück zum Zitat Scheiderer R, Belden C, Schwab D et al (2013) Exercise guidelines for inpatients following ventricular assist device placement: a systematic review of the literature. Cardiopulm Phys Ther J 24(2):35–42PubMedPubMedCentral Scheiderer R, Belden C, Schwab D et al (2013) Exercise guidelines for inpatients following ventricular assist device placement: a systematic review of the literature. Cardiopulm Phys Ther J 24(2):35–42PubMedPubMedCentral
30.
Zurück zum Zitat Piepoli MF, Conraads V, Corrà U et al (2011) Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail 13(4):347–357PubMed Piepoli MF, Conraads V, Corrà U et al (2011) Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail 13(4):347–357PubMed
31.
Zurück zum Zitat Conraads VM, Beckers PJ (2010) Exercise training in heart failure: practical guidance. Heart 96(24):2025–2031PubMed Conraads VM, Beckers PJ (2010) Exercise training in heart failure: practical guidance. Heart 96(24):2025–2031PubMed
32.
Zurück zum Zitat Carvalho VO, Mezzani A (2011) Aerobic exercise training intensity in patients with chronic heart failure: principles of assessment and prescription. Eur J Cardiovasc Prev Rehabil 18(1):5–14PubMed Carvalho VO, Mezzani A (2011) Aerobic exercise training intensity in patients with chronic heart failure: principles of assessment and prescription. Eur J Cardiovasc Prev Rehabil 18(1):5–14PubMed
33.
Zurück zum Zitat Borg G, Noble BJ (1974) Perceived exertion Exercise and Sportn Sciences. Review. JH Wilmore. Academic Press, London Borg G, Noble BJ (1974) Perceived exertion Exercise and Sportn Sciences. Review. JH Wilmore. Academic Press, London
34.
Zurück zum Zitat Carvalho VO, Bocchi EA, Guimarães GV (2009) The Borg scale as an important tool of self-monitoring and selfregulation of exercise prescription in heart failure patients during hydrotherapy. A randomized blinded controlled trial. Circ J 73(10):1871–1876PubMed Carvalho VO, Bocchi EA, Guimarães GV (2009) The Borg scale as an important tool of self-monitoring and selfregulation of exercise prescription in heart failure patients during hydrotherapy. A randomized blinded controlled trial. Circ J 73(10):1871–1876PubMed
35.
Zurück zum Zitat Joo KC, Brubaker PH, MacDougall A et al (2004) Exercise prescription using resting heart rate plus 20 or perceived exertion in cardiac rehabilitation. J Cardpulm Rehabil 24(3):178–184 Joo KC, Brubaker PH, MacDougall A et al (2004) Exercise prescription using resting heart rate plus 20 or perceived exertion in cardiac rehabilitation. J Cardpulm Rehabil 24(3):178–184
36.
Zurück zum Zitat Wasserman K, Mcilroy MB (1964) Detecting the threshold of anaerobic metabolism in cardiac patients during exercise. Am J Cardiol 14:844–852PubMed Wasserman K, Mcilroy MB (1964) Detecting the threshold of anaerobic metabolism in cardiac patients during exercise. Am J Cardiol 14:844–852PubMed
37.
Zurück zum Zitat Beaver WL, Wasserman K, Whipp BJ (1986) A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60(6):2020–2027PubMed Beaver WL, Wasserman K, Whipp BJ (1986) A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60(6):2020–2027PubMed
38.
Zurück zum Zitat Feldman D, Pamboukian SV, Teuteberg JJ et al (2013) International Society for Heart and Lung Transplantation. The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary. J Heart Lung Transplant 32(2):157–187PubMed Feldman D, Pamboukian SV, Teuteberg JJ et al (2013) International Society for Heart and Lung Transplantation. The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary. J Heart Lung Transplant 32(2):157–187PubMed
39.
Zurück zum Zitat Hasin T, Topilsky Y, Kremers WK et al (2012) Usefulness of the six-minute walkt est after continuous axial flow left ventricular device implantation to predict survival. Am J Cardiol 110(9):1322–1328PubMedPubMedCentral Hasin T, Topilsky Y, Kremers WK et al (2012) Usefulness of the six-minute walkt est after continuous axial flow left ventricular device implantation to predict survival. Am J Cardiol 110(9):1322–1328PubMedPubMedCentral
40.
Zurück zum Zitat Stainback RF, Estep JD, Agler DA et al (2015) American Society of Echocardiography. Echocardiography in the management of patients with left ventricular assist devices: Recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr 28(8):853–909PubMed Stainback RF, Estep JD, Agler DA et al (2015) American Society of Echocardiography. Echocardiography in the management of patients with left ventricular assist devices: Recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr 28(8):853–909PubMed
41.
Zurück zum Zitat Estep JD, Stainback RF, Little SH et al (2010) The role of echocardiography and other imaging modalities in patients with left ventricular assist devices. JACC Cardiovasc Imaging 3(10):1049–1064PubMed Estep JD, Stainback RF, Little SH et al (2010) The role of echocardiography and other imaging modalities in patients with left ventricular assist devices. JACC Cardiovasc Imaging 3(10):1049–1064PubMed
42.
Zurück zum Zitat Mookadam F, Kendall CB, Wong RK et al (2012) Left ventricular assist devices: physiologic assessment using echocardiography for management and optimization. Ultrasound Med Biol 38(2):335–345PubMed Mookadam F, Kendall CB, Wong RK et al (2012) Left ventricular assist devices: physiologic assessment using echocardiography for management and optimization. Ultrasound Med Biol 38(2):335–345PubMed
43.
Zurück zum Zitat Wonisch M, Berent R, Klicpera M, Laimer H, Marko C, Pokan R, Schmid P, Schwann H (2008) Praxisleitlinien Ergometrie. J Kardiol 15(Suppl A):2–17 Wonisch M, Berent R, Klicpera M, Laimer H, Marko C, Pokan R, Schmid P, Schwann H (2008) Praxisleitlinien Ergometrie. J Kardiol 15(Suppl A):2–17
44.
Zurück zum Zitat Givertz MM (2011) Cardiology patient pages: ventricular assist devices: importantinformation for patients and families. Circulation 124(12):e305–e311PubMed Givertz MM (2011) Cardiology patient pages: ventricular assist devices: importantinformation for patients and families. Circulation 124(12):e305–e311PubMed
45.
Zurück zum Zitat Marko C, Danzinger G, Käferbäck M et al (2015) Safety and efficacy of cardiac rehabilitation for patients with continuous flow left ventricular assist devices. Eur J Prev Cardiol 22(11):1378–1384PubMed Marko C, Danzinger G, Käferbäck M et al (2015) Safety and efficacy of cardiac rehabilitation for patients with continuous flow left ventricular assist devices. Eur J Prev Cardiol 22(11):1378–1384PubMed
46.
Zurück zum Zitat Marko C, Xhelili E, Lackner T et al (2017) Exercise performance during the first two years after left ventricular assist device implantation. ASAIO J 63(4):408–413PubMedPubMedCentral Marko C, Xhelili E, Lackner T et al (2017) Exercise performance during the first two years after left ventricular assist device implantation. ASAIO J 63(4):408–413PubMedPubMedCentral
47.
Zurück zum Zitat Adamopoulos S, Corrà U, Laoutaris ID et al (2019) Exercise training in patients with ventricular assist devices: a review of the evidence and practical advice. A position paper from the Committee on Exercise Physiology and Training and the Committee of Advanced Heart Failure of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 21(1):3–13PubMed Adamopoulos S, Corrà U, Laoutaris ID et al (2019) Exercise training in patients with ventricular assist devices: a review of the evidence and practical advice. A position paper from the Committee on Exercise Physiology and Training and the Committee of Advanced Heart Failure of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 21(1):3–13PubMed
48.
Zurück zum Zitat Corrà U, Pistono M (2019) Early mobilization in LVAD recipients: an obligatory step towards recovery. Monaldi Arch Chest Dis 89(1):e967–e989 Corrà U, Pistono M (2019) Early mobilization in LVAD recipients: an obligatory step towards recovery. Monaldi Arch Chest Dis 89(1):e967–e989
49.
Zurück zum Zitat Abshire M, Dennison Himmelfarb CR, Russell SD (2014) Functional status in left ventricular assist device-supported patients: a literature review. J Card Fail 20(12):973–983PubMedPubMedCentral Abshire M, Dennison Himmelfarb CR, Russell SD (2014) Functional status in left ventricular assist device-supported patients: a literature review. J Card Fail 20(12):973–983PubMedPubMedCentral
50.
Zurück zum Zitat Ganga HV, Leung A, Jantz J et al (2017) Supervised exercise training versus usual care in ambulatory patients with left ventricular assist devices: a systematic review. PLoS One 12(3):e0174323PubMedPubMedCentral Ganga HV, Leung A, Jantz J et al (2017) Supervised exercise training versus usual care in ambulatory patients with left ventricular assist devices: a systematic review. PLoS One 12(3):e0174323PubMedPubMedCentral
51.
Zurück zum Zitat Mahfood Haddad T, Saurav A, Smer A et al (2017) Cardiac rehabilitation in patients with left ventricular assist device: a systematic review and meta-analysis. J Cardiopulm Rehabil Prev 37(6):390–396PubMed Mahfood Haddad T, Saurav A, Smer A et al (2017) Cardiac rehabilitation in patients with left ventricular assist device: a systematic review and meta-analysis. J Cardiopulm Rehabil Prev 37(6):390–396PubMed
52.
Zurück zum Zitat Marconi C, Marzorati M (2003) Exercise after heart transplantation. Eur J Appl Physiol 990:250–259 Marconi C, Marzorati M (2003) Exercise after heart transplantation. Eur J Appl Physiol 990:250–259
53.
Zurück zum Zitat Kavanagh T (2005) Exercise rehabilitation in cardiac transplantation patients: a comprehensive review. Eur Med J 41:67–74 Kavanagh T (2005) Exercise rehabilitation in cardiac transplantation patients: a comprehensive review. Eur Med J 41:67–74
54.
Zurück zum Zitat Haberbusch M, De Luca D, Moscato F (2020) Changes in resting and exercise hemodynamics early after heart transplantation: a simulation perspective. Front Physiol 11:579449PubMedPubMedCentral Haberbusch M, De Luca D, Moscato F (2020) Changes in resting and exercise hemodynamics early after heart transplantation: a simulation perspective. Front Physiol 11:579449PubMedPubMedCentral
55.
Zurück zum Zitat Bengel FM, Ueberfuhr P, Hesse T, Schiepel N, Ziegler SI, Scholz S, Nekolla SG, Reichard B, Schwaiger M (2002) Clinical determinants of ventricular sympathetic reinnervation after orthotopic heart transplantation. Circulation 106:831–835PubMed Bengel FM, Ueberfuhr P, Hesse T, Schiepel N, Ziegler SI, Scholz S, Nekolla SG, Reichard B, Schwaiger M (2002) Clinical determinants of ventricular sympathetic reinnervation after orthotopic heart transplantation. Circulation 106:831–835PubMed
56.
Zurück zum Zitat Ueberfur P, Ziegler S, Schwaiblmair M, Reichart B, Schwaiger M (2000) Incomplete sympathetic reinnervation of the orthotopic transplanted human heart: observation up to 13 years after heart transplantation. Eur J Cardiothorac Surg 17:161–168 Ueberfur P, Ziegler S, Schwaiblmair M, Reichart B, Schwaiger M (2000) Incomplete sympathetic reinnervation of the orthotopic transplanted human heart: observation up to 13 years after heart transplantation. Eur J Cardiothorac Surg 17:161–168
57.
Zurück zum Zitat Braith RW (1998) Exercise training in patients with CHF and heart transplant recipients. Med Sci Sports Exerc 30:367–378 Braith RW (1998) Exercise training in patients with CHF and heart transplant recipients. Med Sci Sports Exerc 30:367–378
58.
Zurück zum Zitat Pokan R, von Duvillard SP, Ludwig J, Rohrer A, Hofmann P, Wonisch M, Smekal G, Schmid P, Pacher R, Bachl N (2004) Effect of high volume and intensity endurance training in heart transplant recipients. Med Sci Sports Exerc 36(12):2011–2016PubMed Pokan R, von Duvillard SP, Ludwig J, Rohrer A, Hofmann P, Wonisch M, Smekal G, Schmid P, Pacher R, Bachl N (2004) Effect of high volume and intensity endurance training in heart transplant recipients. Med Sci Sports Exerc 36(12):2011–2016PubMed
59.
Zurück zum Zitat Geny B, Richard R, Zoll J, Charloux A, Piquard F (2008) Last word on Point: Counterpoint: Cardiac denervation does/does not Play a major role in exercise limitation after heart transplantation. J Appl Physiol 249:568 Geny B, Richard R, Zoll J, Charloux A, Piquard F (2008) Last word on Point: Counterpoint: Cardiac denervation does/does not Play a major role in exercise limitation after heart transplantation. J Appl Physiol 249:568
60.
Zurück zum Zitat Iglesias D, Masson W, Barbagelata L, Rossi E, Mora M, Cornejo G, Lagoria J, Belziti C, Vulcano N, Marenchino R, Pizarro R, Ventura H (2021) Prognostic value of cardiopulmonary exercise test after heart transplantation. Clin Transpl 35(8):e14387. https://doi.org/10.1111/ctr.14387. Epub 2021 Jun 28CrossRef Iglesias D, Masson W, Barbagelata L, Rossi E, Mora M, Cornejo G, Lagoria J, Belziti C, Vulcano N, Marenchino R, Pizarro R, Ventura H (2021) Prognostic value of cardiopulmonary exercise test after heart transplantation. Clin Transpl 35(8):e14387. https://​doi.​org/​10.​1111/​ctr.​14387. Epub 2021 Jun 28CrossRef
61.
Zurück zum Zitat Dall CH, Gustafsson F, Christensen SB, Dela F, Langberg H, Prescott E (2015) Effect of moderate- versus high-intensity exercise on vascular function, biomarkers and quality of life in heart transplant recipients: a randomized, crossover trial. J Heart Lung Transplant 34:1033–1041PubMed Dall CH, Gustafsson F, Christensen SB, Dela F, Langberg H, Prescott E (2015) Effect of moderate- versus high-intensity exercise on vascular function, biomarkers and quality of life in heart transplant recipients: a randomized, crossover trial. J Heart Lung Transplant 34:1033–1041PubMed
62.
Zurück zum Zitat Nytroen K, Rolid K, Andreassen AK, Yardley M, Gude E, Dahle DO et al (2019) Effect of highintensity interval training in De novo heart transplant recipients in Scandinavia. Circulation 139:2198–2211PubMed Nytroen K, Rolid K, Andreassen AK, Yardley M, Gude E, Dahle DO et al (2019) Effect of highintensity interval training in De novo heart transplant recipients in Scandinavia. Circulation 139:2198–2211PubMed
64.
Zurück zum Zitat Guimarãe GV, Ribeiro F, Arthuso FZ, Castro RE, Cornelissen V, Ciolac EG (2021) Contemporary review of exercise in heart transplant recipients. Transplant Rev 35:100597 Guimarãe GV, Ribeiro F, Arthuso FZ, Castro RE, Cornelissen V, Ciolac EG (2021) Contemporary review of exercise in heart transplant recipients. Transplant Rev 35:100597
65.
Zurück zum Zitat Wonisch M, Marko C, Niebauer J, Pokan R, Schmid P, Wiesinger E (2012) Bedeutung des Krafttrainings zur Prävention und Rehabilitation internistischer Erkrankungen. Wien Klin Wochenschr 124:326–333PubMed Wonisch M, Marko C, Niebauer J, Pokan R, Schmid P, Wiesinger E (2012) Bedeutung des Krafttrainings zur Prävention und Rehabilitation internistischer Erkrankungen. Wien Klin Wochenschr 124:326–333PubMed
66.
Zurück zum Zitat Hiksen R, Marone JR (1993) Exercise and inhibition of glucocorticoid-induced muscle atrophy. Exerc Sport Sci Rev 21:135–167 Hiksen R, Marone JR (1993) Exercise and inhibition of glucocorticoid-induced muscle atrophy. Exerc Sport Sci Rev 21:135–167
67.
Zurück zum Zitat Niebauer J, Tschentscher M, Mayr C, Pokan R, Benzer W (2013) Outpatient cardiac rehabilitation: the Austrian model. Eur J Prev Cardiol 20(3):468–479PubMed Niebauer J, Tschentscher M, Mayr C, Pokan R, Benzer W (2013) Outpatient cardiac rehabilitation: the Austrian model. Eur J Prev Cardiol 20(3):468–479PubMed
68.
Zurück zum Zitat Hsieh PL, Wu YT, Chao WJ (2011) Effects of exercise training in heart transplant recipients: a meta-analysis. Cardiology 120(1):27–35PubMed Hsieh PL, Wu YT, Chao WJ (2011) Effects of exercise training in heart transplant recipients: a meta-analysis. Cardiology 120(1):27–35PubMed
69.
Zurück zum Zitat Haykowsky M, Tymchak W (2007) Superior athletic performance two decades after cardiac transplantation. N Engl J Med 356:2007–2008PubMed Haykowsky M, Tymchak W (2007) Superior athletic performance two decades after cardiac transplantation. N Engl J Med 356:2007–2008PubMed
Metadaten
Titel
Training von Patienten mit linksventrikulären mechanischen und nach
verfasst von
Christiane Marko
Francesco Moscato
Rochus Pokan
Copyright-Jahr
2023
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-65165-0_26

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Knie-TEP: Kein Vorteil durch antibiotikahaltigen Knochenzement

29.05.2024 Periprothetische Infektionen Nachrichten

Zur Zementierung einer Knie-TEP wird in Deutschland zu über 98% Knochenzement verwendet, der mit einem Antibiotikum beladen ist. Ob er wirklich besser ist als Zement ohne Antibiotikum, kann laut Registerdaten bezweifelt werden.

Häusliche Gewalt in der orthopädischen Notaufnahme oft nicht erkannt

28.05.2024 Häusliche Gewalt Nachrichten

In der Notaufnahme wird die Chance, Opfer von häuslicher Gewalt zu identifizieren, von Orthopäden und Orthopädinnen offenbar zu wenig genutzt. Darauf deuten die Ergebnisse einer Fragebogenstudie an der Sahlgrenska-Universität in Schweden hin.

Fehlerkultur in der Medizin – Offenheit zählt!

28.05.2024 Fehlerkultur Podcast

Darüber reden und aus Fehlern lernen, sollte das Motto in der Medizin lauten. Und zwar nicht nur im Sinne der Patientensicherheit. Eine negative Fehlerkultur kann auch die Behandelnden ernsthaft krank machen, warnt Prof. Dr. Reinhard Strametz. Ein Plädoyer und ein Leitfaden für den offenen Umgang mit kritischen Ereignissen in Medizin und Pflege.

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.