Erschienen in:
21.12.2023 | Editorial
Selective decontamination of the digestive tract: it’s all in your mind!
verfasst von:
Pieter Depuydt, Nicolas Molinari, Romain Sonneville
Erschienen in:
Intensive Care Medicine
|
Ausgabe 1/2024
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Excerpt
Selective decontamination of the digestive tract (SDD) consists of the application of topical, non-absorbable antibiotics in the mouth and digestive tract, most often accompanied by a short intravenous course of antibiotics without anaerobic spectrum, with the aim to eradicate potentially pathogenic bacteria (mostly Staphylococcus aureus and Gram-negative aerobic rods) and yeasts from the gut while preserving the resident anaerobic flora. The debate whether SDD should be universally adopted to prevent nosocomial infections and improve outcome of patients receiving invasive mechanical ventilation in the intensive care unit (ICU) has been ongoing for over 3 decades, as this intervention could theoretically be associated with increased antimicrobial resistance. …