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08.04.2023 | Original Article

Lowering the percent body fat in the obese population might reduce male lower urinary tract symptoms

verfasst von: Jooho Lee, Jung Hoon Lee, Min Soo Choo, Min Chul Cho, Hwancheol Son, Hyeon Jeong, Ji Bong Jeong, Sangjun Yoo

Erschienen in: World Journal of Urology | Ausgabe 6/2023

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Abstract

Purpose

This study aimed to investigate the practicality of percent body fat (PBF), calculated using bioelectrical impedance analysis (BIA), in predicting benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS).

Methods

This study included 844 men who underwent medical checkups at our institution between 2014 and 2022. Demographic characteristics, serum PSA levels, and prostate volume were collected using TRUS. BPH was defined as a prostate volume ≥ 30 cc. Subjects were divided into two groups according to their quartiles of PBF: the normal PBF group (first to third quartile; PBF < 27.9%) and the high PBF group (fourth quartile; PBF ≥ 27.9%). Characteristics between the groups were compared using the chi-square test and Student’s t-test. Multivariate logistic regression analysis was performed to evaluate risk factors for BPH and severe LUTS.

Results

The prostate volume (25.21 ± 8.4 vs 27.30 ± 9.0, p = 0.005) and percentage of BPH (22.9% vs. 32.1%, p = 0.007) were greater in the high PBF group. After multivariate analysis, old age (OR = 1.066, p < 0.001), higher appendicular skeletal muscle mass index (ASMI) (OR = 1.544, p = 0.001), and PBF ≥ 27.9% (OR = 1.455, p = 0.037) were risk factors for BPH. Larger prostate volume (OR = 1.035, p = 0.002) and PBF ≥ 27.9% (OR = 1.715, p = 0.025) were risk factors for severe LUTS. However, a greater ASMI had a protective effect against severe LUTS (OR = 0.654, p = 0.011).

Conclusions

This study shows that PBF and ASMI are useful for predicting BPH/LUTS. We suggest that lowering PBF to the normal range in a population with high PBF might prevent BPH, while lowering PBF and maintaining adequate ASMI could lower LUTS.

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Titel: Lowering the percent body fat in the obese population might reduce male lower urinary tract symptoms
verfasst von: Jooho Lee
Jung Hoon Lee
Min Soo Choo
Min Chul Cho
Hwancheol Son
Hyeon Jeong
Ji Bong Jeong
Sangjun Yoo
Publikationsdatum: 08.04.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: World Journal of Urology / Ausgabe 6/2023
Print ISSN: 0724-4983
Elektronische ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-023-04397-w

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Lowering the percent body fat in the obese population might reduce male lower urinary tract symptoms