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Indian Journal of Otolaryngology and Head & Neck Surgery
Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery 2/2022

25.11.2020 | Clinical Report

Lacrimal Gland Adenoid Cystic Carcinoma with High Grade Transformation: A Case Report and Current Concepts in Multi Modality Management

verfasst von: Siddharth A. Shah, Loma Parikh, Raghuvir Solanki, Jatin Bhojani, Raviraj Gohil

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Sonderheft 2/2022

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Abstract

Lacrimal gland adenoid cystic carcinoma (AdCC) is associated with an aggressive clinical course and grave prognosis. A high grade transformation within adenoid cystic carcinoma of lacrimal gland is a rare condition which is even more locally aggressive with frequent neck and distant metastasis. We present a case of left lacrimal gland adenoid cystic carcinoma with high grade transformation to adenocarcinoma NOS type presenting with orbital pain and proptosis. After thorough evaluation for locoregional and distant spread of the disease, the patient underwent left orbital exenteration with orbitectomy and neck dissection with free flap reconstruction. Patient received adjuvant radiation therapy and is presently disease free for last 6 months. A multi-modality management protocol involving surgery, radiotherapy and chemotherapy has been proposed for management of lacrimal gland AdCC with high grade transformation. We report the 4th case in the literature of lacrimal gland adenoid cystic carcinoma with high grade transformation.
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Metadaten
Titel
Lacrimal Gland Adenoid Cystic Carcinoma with High Grade Transformation: A Case Report and Current Concepts in Multi Modality Management
verfasst von
Siddharth A. Shah
Loma Parikh
Raghuvir Solanki
Jatin Bhojani
Raviraj Gohil
Publikationsdatum
25.11.2020
Verlag
Springer India
Erschienen in
Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe Sonderheft 2/2022
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-020-02277-y

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