Atypical haemolytic-uraemic syndrome (aHUS) is a form of thrombotic microangiopathy (TMA) associated with dysregulation of the alternative complement pathway [ 1 – 3 ]. It is characterized by microangiopathic haemolytic anaemia (MAHA) …
Acute kidney injury (AKI) is a broad clinical syndrome characterized by an abrupt reduction in glomerular filtration and/or reduced urinary output [ 1 – 4 ], and almost all of the epidemiological information about AKI has focused on hospitalized …
Kidney transplant outcomes are influenced by factors including donor age and sex, whether the donor is living or deceased, clinical era of transplant, donor cause of death, and HLA mismatch [ 1 , 2 ]. It is well established that organs from living …
verfasst von:
Kane E. Collins, Edmund Gilbert, Vincent Mauduit, Katherine A. Benson, Elhussein A. E. Elhassan, Conall O’Seaghdha, Claire Hill, Amy Jayne McKnight, Alexander P. Maxwell, Peter J. van der Most, Martin H. de Borst, Weihua Guan, Pamala A. Jacobson, Ajay K. Israni, Brendan J. Keating, Graham M. Lord, Salla Markkinen, Ilkka Helanterä, Kati Hyvärinen, Jukka Partanen, Stephen F. Madden, Sophie Limou, Gianpiero L. Cavalleri, Peter J. Conlon
Chronic kidney disease (CKD) can lead to disability and is associated with premature death, particularly due to cardiovascular factors. A person is said to have CKD when their kidneys have had abnormal structure and function for > 3 months [ 1 ].
verfasst von:
Angela Beros, John Sluyter, Alun Hughes, Bernhard Hametner, Siegfried Wassertheurer, Robert Scragg
Claudia Morganti, Tommaso Di Motta, Andrea Andreone, Stella Bedogni, Sara Alibrandi, Giuseppe Benigno, Ilaria Paladini, Enrico Epifani, Enrico Fiaccadori, Umberto Maggiore
The World Health Organization declared the coronavirus disease 2019 (COVID-19) a global pandemic in March 2020. In Greece, the first lockdown lasted almost two months, from the middle of March 2020 until the first days of May 2020, while the …
verfasst von:
Vassiliki Michou, Maria Nikodimopoulou, Vassilios Liakopoulos, Maria Anifanti, Georgios Tsamos, Dimitra Vasdeki, George Panayiotou, Dimitra Mameletzi, Asterios Deligiannis, Evangelia Kouidi
29.05.2024 | Lessons for the Clinical Nephrologist
A 37-year-old man presented with progressively worsening kidney function and proteinuria. Approximately 7 years earlier, he had episodes of lower back pain and intense abdominal pain, leading to multiple visits to the emergency department, but no …
verfasst von:
Marco Allinovi, Lorenzo Salvati, Brunilda Xhaferi, Linda Di Pietro, Simone Annicchiarico, Marco Del Carria, Federico Perfetto, Franco Bergesio, Paola Parronchi
We present the case of a 58-year-old male diabetic patient admitted to our department for a slight decrease in kidney function, with nephrotic range proteinuria, hematuria (16,000/ml) and positive anti-glomerular basement membrane antibodies.
The impact of the COVID-19 pandemic on solid organ transplant recipients and on transplantation activity has been highly negative. Indeed, solid organ transplant recipients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
verfasst von:
Simona Simone, Virginia Pronzo, Francesco Pesce, Davide Fiore Bavaro, Barbara Infante, Silvia Mercuri, Annalisa Schirinzi, Antonella Panaro, Eleonora Conte, Alessandra Belati, Dario Troise, Paola Pontrelli, Francesca Conserva, Pasquale Gallo, Maddalena Panico, Marco Spilotros, Giuseppe Lucarelli, Annalisa Saracino, Giovanni Stallone, Francesca Di Serio, Pasquale Ditonno, Loreto Gesualdo
The quest to accurately gauge kidney function has been a persistent undertaking in the medical community, with the glomerular filtration rate (GFR) standing as the definitive indicator of renal health. The historical trajectory of estimating GFR …
ChatGPT, a prominent large language model (LLM) developed by OpenAI, emerged at the end of 2022. Distinct from its predecessor GPT-3.5, the latest iteration, GPT-4, is equipped with advanced functionalities encompassing both textual and visual …
verfasst von:
Jing Miao, Charat Thongprayoon, Iasmina M. Craici, Wisit Cheungpasitporn
The majority of end-stage kidney disease patients are treated with haemodialysis (HD). Starting HD can pose physical, social, and psychological challenges to patients, and mortality rates within the first 6 months are disproportionately high, with …
verfasst von:
Usama Butt, A. Davenport, S. Sridharan, K. Farrington, E. Vilar
We report a successful, albeit complicated pregnancy with a live-born healthy baby at 28 weeks' gestation, after 10 pregnancy failures, in a 39-year-old patient with a history of liver transplantation and chronic kidney disease with hypertension …
verfasst von:
Leonard Cauchy, Eve Mousty, George-Philippe Pageaux, Olivier Moranne
On January 30, 2020, the World Health Organization (WHO) declared the outbreak of the COVID-19 virus a ‘public health emergency of international concern’ and shortly thereafter a pandemic [ 1 , 2 ]. In response, healthcare systems worldwide …
verfasst von:
Joan Fernando, Ignacio Revuelta, Eva Palou, Rosario Scandurra, Beatriu Bayés, Joan Escarrabill
Hemophagocytic syndrome is a disease resulting from an excessive pathological inflammatory response caused by immune dysfunction, which can lead to cytokine storms and widespread organ dysfunction, including kidney injury. Renal involvement …
Rossella Attini, Gianfranca Cabiddu, Francesca Ciabatti, Benedetta Montersino, Andrea Roberto Carosso, Giuseppe Gernone, Linda Gammaro, Gabriella Moroni, Massimo Torreggiani, Bianca Masturzo, Domenico Santoro, Alberto Revelli, Giorgina Barbara Piccoli, On behalf of the Italian Society of Nephrology’s Project Group on Kidney and Pregnancy
Chronic kidney disease (CKD) is highly prevalent in the United States, impacting 14% of all adults and approximately 40% of all people over the age of 65 [ 1 ]. Progression to end-stage kidney disease (kidney failure) and dialysis treatment results …
verfasst von:
Eleanor Rivera, Nathan Tintle, Raymond R. Townsend, Mahboob Rahman, Sarah J. Schrauben, Maya N. Clark-Cutaia, Mary Hannan, James P. Lash, Katherine Wolfrum, Celestin Missikpode, Karen B. Hirschman
