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Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery 2/2022

01.09.2020 | Original Article

Correlation Between Allergic Rhinitis and Body Mass Index: An Observational Study

verfasst von: Anil S. Harugop, Akriti Walia, Rajesh Radhakrishna Havaldar, R. S. Mudhol

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Sonderheft 2/2022

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Abstract

Allergic rhinitis is one of the most rampant diseases in the world and many studies have been conducted to find its risk factors. Various studies have shown that there is a correlation between allergic rhinitis and increased Body Mass Index (BMI). Obesity has several effects on the immune system that could play a major role in increasing allergic disease. Allergic rhinitis is known to produce mild eosinophilia. The purpose of this study is to assess the correlation between BMI and allergic rhinitis using the Absolute Eosinophil Count (AEC). Over a period of 6 months, 55 cases of allergic rhinitis were selected. The patients were investigated by Absolute Eosinophil Count and their Body Mass Index values were calculated based on weight and height measurement. There was a positive correlation between Absolute Eosinophil Count and BMI with a p value of < 0.0001 which in turn revealed a positive correlation between BMI and allergy. We conclude that patients with high BMI are more prone to allergic rhinitis and have higher Absolute Eosinophil Counts probably due to the immunological effects of adipose tissue on the progress of the allergic disease.
Literatur
1.
Zurück zum Zitat Singh S, Sharma BB, Salvi S et al (2018) Allergic rhinitis, rhinoconjunctivitis, and eczema: prevalence and associated factors in children. Clin Respir J 12:547–556CrossRefPubMed Singh S, Sharma BB, Salvi S et al (2018) Allergic rhinitis, rhinoconjunctivitis, and eczema: prevalence and associated factors in children. Clin Respir J 12:547–556CrossRefPubMed
3.
Zurück zum Zitat Zmora N, Bashiardes S, Levy M, Elinav E (2017) The role of the immune system in metabolic health and disease. Cell Metab 25(3):506–521CrossRefPubMed Zmora N, Bashiardes S, Levy M, Elinav E (2017) The role of the immune system in metabolic health and disease. Cell Metab 25(3):506–521CrossRefPubMed
5.
Zurück zum Zitat Permaul P, Kanchongkittiphon W, Phipatanakul W (2014) Childhood asthma and obesity—What is the true link? Ann Allergy Asthma Immunol 113:244–246CrossRefPubMedPubMedCentral Permaul P, Kanchongkittiphon W, Phipatanakul W (2014) Childhood asthma and obesity—What is the true link? Ann Allergy Asthma Immunol 113:244–246CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Leiria LO, Martins MA, Saad MJ (2015) Obesity and asthma: beyond T(H)2 inflammation. Metabolism 64:172–181CrossRefPubMed Leiria LO, Martins MA, Saad MJ (2015) Obesity and asthma: beyond T(H)2 inflammation. Metabolism 64:172–181CrossRefPubMed
7.
Zurück zum Zitat Han YY, Forno E, Gogna M, Celedón JC (2016) Obesity and rhinitis in a nationwide study of children and adults in the United States. J Allergy Clin Immunol 137(5):1460–1465CrossRefPubMedPubMedCentral Han YY, Forno E, Gogna M, Celedón JC (2016) Obesity and rhinitis in a nationwide study of children and adults in the United States. J Allergy Clin Immunol 137(5):1460–1465CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Aghadavod E, Mollae H, Nouri M, Hamishehkar H (2017) Evaluation of relationship between BMI with vitamin D receptor gene expression and vitamin D levels of follicular fluid in overweight patients with polycystic ovary syndrome. Int J Fertil Steril 11(2):105–111PubMedPubMedCentral Aghadavod E, Mollae H, Nouri M, Hamishehkar H (2017) Evaluation of relationship between BMI with vitamin D receptor gene expression and vitamin D levels of follicular fluid in overweight patients with polycystic ovary syndrome. Int J Fertil Steril 11(2):105–111PubMedPubMedCentral
9.
Zurück zum Zitat Jain AK (2016) Determination of absolute eosinophil count. In: Jain AK (ed) Manual of practical physiology for MBBS, 5th edn. Arya Publications, India, pp 65–66 Jain AK (2016) Determination of absolute eosinophil count. In: Jain AK (ed) Manual of practical physiology for MBBS, 5th edn. Arya Publications, India, pp 65–66
11.
Zurück zum Zitat Lam YY, Mitchell AJ, Holmes AJ, Denyer GS, Gummesson A, Caterson ID et al (2011) Role of the gut in visceral fat inflammation and metabolic disorders. Obesity 19(11):2113–2120CrossRefPubMed Lam YY, Mitchell AJ, Holmes AJ, Denyer GS, Gummesson A, Caterson ID et al (2011) Role of the gut in visceral fat inflammation and metabolic disorders. Obesity 19(11):2113–2120CrossRefPubMed
12.
Zurück zum Zitat Ciprandi G, Pistorio A, Tosca M, Ferraro MR, Cirillo I (2009) Body mass index, respiratory function and bronchial hyperreactivity in allergic rhinitisand asthma. Respir Med 103(2):289–295CrossRefPubMed Ciprandi G, Pistorio A, Tosca M, Ferraro MR, Cirillo I (2009) Body mass index, respiratory function and bronchial hyperreactivity in allergic rhinitisand asthma. Respir Med 103(2):289–295CrossRefPubMed
13.
Zurück zum Zitat Forno E, Acosta-Perez E, Brehm JM, Han YY, Alvarez M, Colon-Semidey A et al (2014) Obesity and adiposity indicators, asthma and atopy in Puerto Rican children. J Allergy Clin Immunol 133(5):1308–1314CrossRefPubMed Forno E, Acosta-Perez E, Brehm JM, Han YY, Alvarez M, Colon-Semidey A et al (2014) Obesity and adiposity indicators, asthma and atopy in Puerto Rican children. J Allergy Clin Immunol 133(5):1308–1314CrossRefPubMed
14.
Zurück zum Zitat Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW et al (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292–295CrossRefPubMed Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW et al (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292–295CrossRefPubMed
15.
Zurück zum Zitat Kato H, Ueki S, Kamada R, Kihara J, Yamauchi Y et al (2011) Leptin has a priming effect on eotaxin-induced human eosinophil chemotaxis. Int Arch Allergy Immunol 155:335–344CrossRefPubMed Kato H, Ueki S, Kamada R, Kihara J, Yamauchi Y et al (2011) Leptin has a priming effect on eotaxin-induced human eosinophil chemotaxis. Int Arch Allergy Immunol 155:335–344CrossRefPubMed
16.
Zurück zum Zitat Saadeh D, Salameh P, Caillaud D, Charpin D, de Blay F, Kopferschmitt C et al (2014) High body mass index and allergies in schoolchildren: the French sixcities study. BMJ Open Respir Res 1(1):e000054CrossRefPubMedPubMedCentral Saadeh D, Salameh P, Caillaud D, Charpin D, de Blay F, Kopferschmitt C et al (2014) High body mass index and allergies in schoolchildren: the French sixcities study. BMJ Open Respir Res 1(1):e000054CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Paksoy M, Eken M, Aydin S, Alev Oktay Z, Hardal U, Sanli A et al (2010) Theeffects of allergic rhinitis on growth, development and body mass indexesin school children. Indian J Otolaryngol Head Neck Surg 62(1):64–68CrossRefPubMedPubMedCentral Paksoy M, Eken M, Aydin S, Alev Oktay Z, Hardal U, Sanli A et al (2010) Theeffects of allergic rhinitis on growth, development and body mass indexesin school children. Indian J Otolaryngol Head Neck Surg 62(1):64–68CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Conus S, Bruno A, Simon HU (2005) Leptin is an eosinophil survival factor. J Allergy Clin Immunol 116:1228–1234CrossRefPubMed Conus S, Bruno A, Simon HU (2005) Leptin is an eosinophil survival factor. J Allergy Clin Immunol 116:1228–1234CrossRefPubMed
19.
Zurück zum Zitat Vasudevan AR, Wu H, Xydakis AM, Jones PH, Smith EOB et al (2006) Eotaxin and obesity. J Clin Endocrinol Metab 91:256–261CrossRefPubMed Vasudevan AR, Wu H, Xydakis AM, Jones PH, Smith EOB et al (2006) Eotaxin and obesity. J Clin Endocrinol Metab 91:256–261CrossRefPubMed
20.
Zurück zum Zitat Kim HJ, Kim CH, Lee DH, Han MW, Kim MY et al (2011) Expression of eotaxin in 3T3-L1 adipocytes and the effects of weight loss in high-fat diet induced obese mice. Nutr Res Pract 5:11–19CrossRefPubMedPubMedCentral Kim HJ, Kim CH, Lee DH, Han MW, Kim MY et al (2011) Expression of eotaxin in 3T3-L1 adipocytes and the effects of weight loss in high-fat diet induced obese mice. Nutr Res Pract 5:11–19CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Engeli S, Feldpausch M, Gorzelniak K, Hartwig F, Heintze U et al (2003) Association between adiponectin and mediators of inflammation in obese women. Diabetes 52:942–947CrossRefPubMed Engeli S, Feldpausch M, Gorzelniak K, Hartwig F, Heintze U et al (2003) Association between adiponectin and mediators of inflammation in obese women. Diabetes 52:942–947CrossRefPubMed
22.
Zurück zum Zitat Vieira VJ, Ronan AM, Windt MR, Tagliaferro AR (2005) Elevated atopy in healthy obese women. Am J Clin Nutr 82(3):504–509CrossRefPubMed Vieira VJ, Ronan AM, Windt MR, Tagliaferro AR (2005) Elevated atopy in healthy obese women. Am J Clin Nutr 82(3):504–509CrossRefPubMed
23.
Zurück zum Zitat Wang L, Wang K, Gao X, Paul TK, Cai J, Wang Y (2015) Sex difference inthe association between obesity and asthma in US adults: findings from anational study. Respir Med 109(8):955–962CrossRefPubMed Wang L, Wang K, Gao X, Paul TK, Cai J, Wang Y (2015) Sex difference inthe association between obesity and asthma in US adults: findings from anational study. Respir Med 109(8):955–962CrossRefPubMed
Metadaten
Titel
Correlation Between Allergic Rhinitis and Body Mass Index: An Observational Study
verfasst von
Anil S. Harugop
Akriti Walia
Rajesh Radhakrishna Havaldar
R. S. Mudhol
Publikationsdatum
01.09.2020
Verlag
Springer India
Erschienen in
Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe Sonderheft 2/2022
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-020-02095-2

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