Skip to main content

2020 | OriginalPaper | Buchkapitel

19. Chirurgische Therapie von Fisteln

verfasst von : Christoph Holmer, Martin E. Kreis

Erschienen in: Chronisch-entzündliche Darmerkrankungen

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Das Lebenszeitrisiko an einer Fistel zu erkranken ist beim Morbus Crohn bis zu 40 % hoch. Eine differenzierte Fisteltherapie ist in Anbetracht des komplexen Krankheitsbildes für den Therapieerfolg entscheidend. Während bei nichtperianalen Fisteln unter Respektierung Crohn-chirurgischer Prinzipien überwiegend resezierende Verfahren zur Anwendung kommen, ist die Therapie perianaler Fisteln weitaus komplexer und reicht von einfachen Fistelspaltungen über die Anlage von Fadendrainagen bis hin zu aufwendigen plastischen Fistelverschlüssen. Die Ergebnisse neuerer Therapien wie z. B. die mesenchymale Stammzelltherapie bei komplexen Analfisteln sind vielversprechend. Die Kombination aus medikamentöser und chirurgischer Therapie bietet in der Regel die besten Heilungschancen, sodass jegliche Therapie in enger Zusammenarbeit zwischen Gastroenterologen und Chirurgen erfolgen sollte.
Das Kapitel präsentiert die wesentlichen Aspekte der chirurgischen Therapie von Crohn-assoziierten Fisteln.
Literatur
Zurück zum Zitat Abel ME, Chiu YS, Russell TR, Volpe PA (1993) Autologous fibrin glue in the treatment of rectovaginal and complex fistulas. Dis Colon Rectum 36(5):447–449PubMed Abel ME, Chiu YS, Russell TR, Volpe PA (1993) Autologous fibrin glue in the treatment of rectovaginal and complex fistulas. Dis Colon Rectum 36(5):447–449PubMed
Zurück zum Zitat Antakia R, Shorthouse AJ, Robinson K, Lobo AJ (2013) Combined modality treatment for complex fistulating perianal Crohn’s disease. Colorectal Dis 15(2):210–216PubMed Antakia R, Shorthouse AJ, Robinson K, Lobo AJ (2013) Combined modality treatment for complex fistulating perianal Crohn’s disease. Colorectal Dis 15(2):210–216PubMed
Zurück zum Zitat Balciscueta Z, Uribe N, Balciscueta I, Andreu-Ballester JC, García-Granero E (2017) Rectal advancement flap for the treatment of complex cryptoglandular anal fistulas: a systematic review and meta-analysis. Int J Colorectal Dis 32(5):599–609PubMed Balciscueta Z, Uribe N, Balciscueta I, Andreu-Ballester JC, García-Granero E (2017) Rectal advancement flap for the treatment of complex cryptoglandular anal fistulas: a systematic review and meta-analysis. Int J Colorectal Dis 32(5):599–609PubMed
Zurück zum Zitat Bemelman WA, Warusavitarne J, Sampietro GM, Serclova Z, Zmora O, Luglio G, de Buck van Overstraeten A, Burke JP, Buskens CJ, Colombo F, Dias JA, Eliakim R, Elosua T, Gecim IE, Kolacek S, Kierkus J, Kolho KL, Lefevre JH, Millan M, Panis Y, Pinkney T, Russell RK, Shwaartz C, Vaizey C, Yassin N, D’Hoore A (2018) ECCO-ESCP consensus on surgery for Crohn’s disease. J Crohns Colitis. 12(1):1–16PubMed Bemelman WA, Warusavitarne J, Sampietro GM, Serclova Z, Zmora O, Luglio G, de Buck van Overstraeten A, Burke JP, Buskens CJ, Colombo F, Dias JA, Eliakim R, Elosua T, Gecim IE, Kolacek S, Kierkus J, Kolho KL, Lefevre JH, Millan M, Panis Y, Pinkney T, Russell RK, Shwaartz C, Vaizey C, Yassin N, D’Hoore A (2018) ECCO-ESCP consensus on surgery for Crohn’s disease. J Crohns Colitis. 12(1):1–16PubMed
Zurück zum Zitat Berry SM, Fischer JE (1994) Enterocutaneous fistulas. Curr Probl Surg 31:469–566PubMed Berry SM, Fischer JE (1994) Enterocutaneous fistulas. Curr Probl Surg 31:469–566PubMed
Zurück zum Zitat Cintron JR, Abcarian H, Chaudhry V, Singer M, Hunt S, Birnbaum E, Mutch MG, Fleshman J (2013) Treatment of fistula-in-ano using a porcine small intestinal submucosa anal fistula plug. Tech Coloproctol 17:187–191PubMed Cintron JR, Abcarian H, Chaudhry V, Singer M, Hunt S, Birnbaum E, Mutch MG, Fleshman J (2013) Treatment of fistula-in-ano using a porcine small intestinal submucosa anal fistula plug. Tech Coloproctol 17:187–191PubMed
Zurück zum Zitat Compton GL, Bartlett M (2014) Perianal disease in pediatric Crohn disease: a review of MRI findings. Pediatr Radiol 44(10):1198–1208 (quiz 1195-1197)PubMed Compton GL, Bartlett M (2014) Perianal disease in pediatric Crohn disease: a review of MRI findings. Pediatr Radiol 44(10):1198–1208 (quiz 1195-1197)PubMed
Zurück zum Zitat de Bruijn H, Maeda Y, Murphy J, Warusavitarne J, Vaizey CJ (2018) Combined laparoscopic and perineal approach to omental interposition repair of complex rectovaginal fistula. Dis Colon Rectum 61(1):140–143PubMed de Bruijn H, Maeda Y, Murphy J, Warusavitarne J, Vaizey CJ (2018) Combined laparoscopic and perineal approach to omental interposition repair of complex rectovaginal fistula. Dis Colon Rectum 61(1):140–143PubMed
Zurück zum Zitat de Groof EJ, Cabral VN, Buskens CJ, Morton DG, Hahnloser D, Bemelman WA, Research committee of the European Society of Coloproctology (2016) Systematic review of evidence and consensus on perianal fistula: an analysis of national and international guidelines. Colorectal Dis 18(4):O119–O134PubMed de Groof EJ, Cabral VN, Buskens CJ, Morton DG, Hahnloser D, Bemelman WA, Research committee of the European Society of Coloproctology (2016) Systematic review of evidence and consensus on perianal fistula: an analysis of national and international guidelines. Colorectal Dis 18(4):O119–O134PubMed
Zurück zum Zitat El-Gazzaz G, Hull T, Mignanelli E, Hammel J, Gurland B, Zutshi M (2010) Analysis of function and predictors of failure in women undergoing repair of Crohn’s related rectovaginal fistula. J Gastrointest Surg 14:824–829PubMed El-Gazzaz G, Hull T, Mignanelli E, Hammel J, Gurland B, Zutshi M (2010) Analysis of function and predictors of failure in women undergoing repair of Crohn’s related rectovaginal fistula. J Gastrointest Surg 14:824–829PubMed
Zurück zum Zitat El-Gazzaz G, Hull T, Church JM (2012) Biological immunomodulators improve the healing rate in surgically treated perianal Crohn’s fistulas. Colorectal Dis 14(10):1217–1223PubMed El-Gazzaz G, Hull T, Church JM (2012) Biological immunomodulators improve the healing rate in surgically treated perianal Crohn’s fistulas. Colorectal Dis 14(10):1217–1223PubMed
Zurück zum Zitat Feng JS, Li JY, Yang Z, Chen XY, Mo JJ, Li SH (2018) Stapled side-to-side anastomosis might be benefit in intestinal resection for Crohn’s disease: a systematic review and network meta-analysis. Medicine (Baltimore). 97(15):e0315PubMedPubMedCentral Feng JS, Li JY, Yang Z, Chen XY, Mo JJ, Li SH (2018) Stapled side-to-side anastomosis might be benefit in intestinal resection for Crohn’s disease: a systematic review and network meta-analysis. Medicine (Baltimore). 97(15):e0315PubMedPubMedCentral
Zurück zum Zitat Fürst A, Schmidbauer C, Swol-Ben J, Iesalnieks I, Schwandner O, Agha A (2008) Gracilis transposition for repair of reccurent anovaginal and rectovaginal fistulas in Crohn’s disease. Int J Colorectal Dis 23(4):349-353 Fürst A, Schmidbauer C, Swol-Ben J, Iesalnieks I, Schwandner O, Agha A (2008) Gracilis transposition for repair of reccurent anovaginal and rectovaginal fistulas in Crohn’s disease. Int J Colorectal Dis 23(4):349-353
Zurück zum Zitat Gingold DS, Murrell ZA, Fleshner PR (2014) A prospective evaluation of the ligation of the intersphincteric tract procedure for complex anal fistula in patients with Crohn’s disease. Ann Surg 260(6):1057–1061PubMed Gingold DS, Murrell ZA, Fleshner PR (2014) A prospective evaluation of the ligation of the intersphincteric tract procedure for complex anal fistula in patients with Crohn’s disease. Ann Surg 260(6):1057–1061PubMed
Zurück zum Zitat Gonsalves S, Sagar P, Lengyel J, Morrison C, Dunham R (2009) Assessment of the efficacy of the rectovaginal button fistula plug for the treatment of ileal pouch-vaginal and rectovaginal fistulas. Dis Colon Rectum 52(11):1877–1881PubMed Gonsalves S, Sagar P, Lengyel J, Morrison C, Dunham R (2009) Assessment of the efficacy of the rectovaginal button fistula plug for the treatment of ileal pouch-vaginal and rectovaginal fistulas. Dis Colon Rectum 52(11):1877–1881PubMed
Zurück zum Zitat Grimaud JC, Munoz-Bongrand N, Siproudhis L, Abramowitz L, Sénéjoux A, Vitton V, Gambiez L, Flourié B, Hébuterne X, Louis E, Coffin B, De Parades V, Savoye G, Soulé JC, Bouhnik Y, Colombel JF, Contou JF, François Y, Mary JY, Lémann M, Groupe d’Etude Thérapeutique des Affections Inflammatoires du Tube Digestif (2010) Fibrin glue is effective healing perianal fistulas in patients with Crohn’s disease. Gastroenterology 138(7):2275–2281PubMed Grimaud JC, Munoz-Bongrand N, Siproudhis L, Abramowitz L, Sénéjoux A, Vitton V, Gambiez L, Flourié B, Hébuterne X, Louis E, Coffin B, De Parades V, Savoye G, Soulé JC, Bouhnik Y, Colombel JF, Contou JF, François Y, Mary JY, Lémann M, Groupe d’Etude Thérapeutique des Affections Inflammatoires du Tube Digestif (2010) Fibrin glue is effective healing perianal fistulas in patients with Crohn’s disease. Gastroenterology 138(7):2275–2281PubMed
Zurück zum Zitat Guo Z, Li Y, Zhu W, Gong J, Li N, Li J (2013) Comparing outcomes between side-to-side anastomosis and other anastomotic configurations after intestinal resection for patients with Crohn’s disease: a meta-analysis. World J Surg 37(4):893–901 Guo Z, Li Y, Zhu W, Gong J, Li N, Li J (2013) Comparing outcomes between side-to-side anastomosis and other anastomotic configurations after intestinal resection for patients with Crohn’s disease: a meta-analysis. World J Surg 37(4):893–901
Zurück zum Zitat Halverson AL, Hull TL, Fazio VW, Church J, Hammel J, Floruta C (2001) Repair of recurrent rectovaginal fistulas. Surgery 130:753–757PubMed Halverson AL, Hull TL, Fazio VW, Church J, Hammel J, Floruta C (2001) Repair of recurrent rectovaginal fistulas. Surgery 130:753–757PubMed
Zurück zum Zitat Hannaway CD, Hull TL (2008) Current considerations in the management of rectovaginal fistula from Crohn’s disease. Colorectal Dis 10:747–755PubMed Hannaway CD, Hull TL (2008) Current considerations in the management of rectovaginal fistula from Crohn’s disease. Colorectal Dis 10:747–755PubMed
Zurück zum Zitat He X, Chen Z, Huang J, Lian L, Rouniyar S, Wu X, Lan P (2014) Stapled side-to-side anastomosis might be better than handsewn end-to-end anastomosis in ileocolic resection for Crohn’s disease: a meta-analysis. Dig Dis Sci 59(7):1544–1551PubMed He X, Chen Z, Huang J, Lian L, Rouniyar S, Wu X, Lan P (2014) Stapled side-to-side anastomosis might be better than handsewn end-to-end anastomosis in ileocolic resection for Crohn’s disease: a meta-analysis. Dig Dis Sci 59(7):1544–1551PubMed
Zurück zum Zitat Hellers G, Bergstrand O, Ewerth S, Holmström B (1980) Occurrence and outcome after primary treatment of anal fistulae in Crohn’s disease. Gut 21(6):525–527PubMedPubMedCentral Hellers G, Bergstrand O, Ewerth S, Holmström B (1980) Occurrence and outcome after primary treatment of anal fistulae in Crohn’s disease. Gut 21(6):525–527PubMedPubMedCentral
Zurück zum Zitat Hirten RP, Shah S, Sachar DB, Colombel JF (2018) The management of intestinal penetrating Crohn’s disease. Inflamm Bowel Dis 24(4):752–765PubMed Hirten RP, Shah S, Sachar DB, Colombel JF (2018) The management of intestinal penetrating Crohn’s disease. Inflamm Bowel Dis 24(4):752–765PubMed
Zurück zum Zitat Kamiński JP, Zaghiyan K, Fleshner P (2017) Increasing experience of ligation of the intersphincteric fistula tract for patients with Crohn’s disease: what have we learned? Colorectal Dis 19(8):750–755PubMed Kamiński JP, Zaghiyan K, Fleshner P (2017) Increasing experience of ligation of the intersphincteric fistula tract for patients with Crohn’s disease: what have we learned? Colorectal Dis 19(8):750–755PubMed
Zurück zum Zitat Laukoetter MG, Mennigen R, Hannig CM, Osada N, Rijcken E, Vowinkel T, Krieglstein CF, Senninger N, Anthoni C, Bruewer M (2011) Intestinal cancer risk in Crohn’s disease: a meta-analysis. J Gastrointest Surg 15(4):576–583PubMed Laukoetter MG, Mennigen R, Hannig CM, Osada N, Rijcken E, Vowinkel T, Krieglstein CF, Senninger N, Anthoni C, Bruewer M (2011) Intestinal cancer risk in Crohn’s disease: a meta-analysis. J Gastrointest Surg 15(4):576–583PubMed
Zurück zum Zitat Legué C, Brochard C, Bessi G, Wallenhorst T, Dewitte M, Siproudhis L, Bouguen G (2018) Outcomes of perianal fistulising Crohn’s disease following anti-TNFα treatment discontinuation. Inflamm Bowel Dis 24(6):1107–1113PubMed Legué C, Brochard C, Bessi G, Wallenhorst T, Dewitte M, Siproudhis L, Bouguen G (2018) Outcomes of perianal fistulising Crohn’s disease following anti-TNFα treatment discontinuation. Inflamm Bowel Dis 24(6):1107–1113PubMed
Zurück zum Zitat Lewis RT, Maron DJ (2010) Anorectal Crohn’s disease. Surg Clin North Am 90(1):83–97PubMed Lewis RT, Maron DJ (2010) Anorectal Crohn’s disease. Surg Clin North Am 90(1):83–97PubMed
Zurück zum Zitat Maccioni F, Al Ansari N, Mazzamurro F, Civitelli F, Viola F, Cucchiara S, Catalano C (2014) Detection of Crohn disease lesions of the small and large bowel in pediatric patients: diagnostic value of MR enterography versus reference examinations. AJR 203(5):W533–W542PubMed Maccioni F, Al Ansari N, Mazzamurro F, Civitelli F, Viola F, Cucchiara S, Catalano C (2014) Detection of Crohn disease lesions of the small and large bowel in pediatric patients: diagnostic value of MR enterography versus reference examinations. AJR 203(5):W533–W542PubMed
Zurück zum Zitat Marzo M, Felice C, Pugliese D, Andrisani G, Mocci G, Armuzzi A, Guidi L (2015) Management of perianal fistulas in Crohn’s disease: an up-to-date review. World J Gastroenterol 21(5):1394–1403PubMedPubMedCentral Marzo M, Felice C, Pugliese D, Andrisani G, Mocci G, Armuzzi A, Guidi L (2015) Management of perianal fistulas in Crohn’s disease: an up-to-date review. World J Gastroenterol 21(5):1394–1403PubMedPubMedCentral
Zurück zum Zitat McNevin MS, Lee PY, Bax TW (2007) Martius flap: an adjunct for repair of complex, low rectovaginal fistula. Am J Surg 193:597–599 (discussion 599)PubMed McNevin MS, Lee PY, Bax TW (2007) Martius flap: an adjunct for repair of complex, low rectovaginal fistula. Am J Surg 193:597–599 (discussion 599)PubMed
Zurück zum Zitat Meinero P, Mori L (2011) Video-assisted anal fistula treatment (VAAFT): a novel sphincter-saving procedure for treating complex anal fistulas. Tech Coloproctol 15:417–422PubMedPubMedCentral Meinero P, Mori L (2011) Video-assisted anal fistula treatment (VAAFT): a novel sphincter-saving procedure for treating complex anal fistulas. Tech Coloproctol 15:417–422PubMedPubMedCentral
Zurück zum Zitat Michelassi F, Stella M, Balestracci T, Giuliante F, Marogna P, Block GE (1993) Incidence, diagnosis, and treatment of enteric and colorectal fistulae in patients with Crohn’s disease. Ann Surg 218:660–666PubMedPubMedCentral Michelassi F, Stella M, Balestracci T, Giuliante F, Marogna P, Block GE (1993) Incidence, diagnosis, and treatment of enteric and colorectal fistulae in patients with Crohn’s disease. Ann Surg 218:660–666PubMedPubMedCentral
Zurück zum Zitat Mueller MH, Geis M, Glatzle J, Kasparek M, Meile TT, Jehle EC, Kreis ME, Zittel TT (2007) Risk of fecal diversion in complicated perianal Crohn’s disease. J Gastrointest Surg. 11(4):529–537PubMedPubMedCentral Mueller MH, Geis M, Glatzle J, Kasparek M, Meile TT, Jehle EC, Kreis ME, Zittel TT (2007) Risk of fecal diversion in complicated perianal Crohn’s disease. J Gastrointest Surg. 11(4):529–537PubMedPubMedCentral
Zurück zum Zitat Nordgren S, Fasth S, Hulten L (1992) Anal fistulas in Crohn’s disease: incidence and outcome of surgical treatment. Int J Colorectal Dis 7(4):214–218PubMed Nordgren S, Fasth S, Hulten L (1992) Anal fistulas in Crohn’s disease: incidence and outcome of surgical treatment. Int J Colorectal Dis 7(4):214–218PubMed
Zurück zum Zitat O’Connor L, Champagne BJ, Ferguson MA, Orangio GR, Schertzer ME, Armstrong DN (2006) Efficacy of anal fistula plug in closure of Crohn’s anorectal fistulas. Dis Colon Rectum 49:1569–1573PubMed O’Connor L, Champagne BJ, Ferguson MA, Orangio GR, Schertzer ME, Armstrong DN (2006) Efficacy of anal fistula plug in closure of Crohn’s anorectal fistulas. Dis Colon Rectum 49:1569–1573PubMed
Zurück zum Zitat Ommer A, Herold A, Joos A, Schmidt C, Weyand G, Bussen D (2012) Gore BioA fistula plug in the treatment of high anal fistulas – initial results from a German multicenter-study. Ger Med Sci 10:Doc13PubMedPubMedCentral Ommer A, Herold A, Joos A, Schmidt C, Weyand G, Bussen D (2012) Gore BioA fistula plug in the treatment of high anal fistulas – initial results from a German multicenter-study. Ger Med Sci 10:Doc13PubMedPubMedCentral
Zurück zum Zitat Panés J, García-Olmo D, Van Assche G, Colombel JF, Reinisch W, Baumgart DC, Dignass A, Nachury M, Ferrante M, Kazemi-Shirazi L, Grimaud JC, de la Portilla F, Goldin E, Richard MP, Leselbaum A, Danese S, ADMIRE CD Study Group Collaborators (2016) Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn’s disease: a phase 3 randomised, double-blind controlled trial. Lancet 388:1281–1290PubMed Panés J, García-Olmo D, Van Assche G, Colombel JF, Reinisch W, Baumgart DC, Dignass A, Nachury M, Ferrante M, Kazemi-Shirazi L, Grimaud JC, de la Portilla F, Goldin E, Richard MP, Leselbaum A, Danese S, ADMIRE CD Study Group Collaborators (2016) Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn’s disease: a phase 3 randomised, double-blind controlled trial. Lancet 388:1281–1290PubMed
Zurück zum Zitat Panés J, García-Olmo D, Van Assche G, Colombel JF, Reinisch W, Baumgart DC, Dignass A, Nachury M, Ferrante M, Kazemi-Shirazi L, Grimaud JC, de la Portilla F, Goldin E, Richard MP, Diez MC, Tagarro I, Leselbaum A, Danese S, ADMIRE CD Study Group Collaborators (2018) Long-term efficacy and safety of stem cell therapy (Cx601) for complex perianal fistulas in patients with Crohn’s disease. Gastroenterology 154(5):1334–1342PubMed Panés J, García-Olmo D, Van Assche G, Colombel JF, Reinisch W, Baumgart DC, Dignass A, Nachury M, Ferrante M, Kazemi-Shirazi L, Grimaud JC, de la Portilla F, Goldin E, Richard MP, Diez MC, Tagarro I, Leselbaum A, Danese S, ADMIRE CD Study Group Collaborators (2018) Long-term efficacy and safety of stem cell therapy (Cx601) for complex perianal fistulas in patients with Crohn’s disease. Gastroenterology 154(5):1334–1342PubMed
Zurück zum Zitat Prosst RL, Joos AK (2016) Short-term outcomes of a novel endoscopic clipping device for closure of the internal opening in 100 anorectal fistulas. Tech Coloproctol 20(11):753–758PubMed Prosst RL, Joos AK (2016) Short-term outcomes of a novel endoscopic clipping device for closure of the internal opening in 100 anorectal fistulas. Tech Coloproctol 20(11):753–758PubMed
Zurück zum Zitat Prosst RL, Herold A, Joos AK, Bussen D, Wehrmann M, Gottwald T, Schurr MO (2012) The anal fistula claw: the OTSC clip for anal fistula closure. Colorectal Dis 14(9):1112–1117PubMed Prosst RL, Herold A, Joos AK, Bussen D, Wehrmann M, Gottwald T, Schurr MO (2012) The anal fistula claw: the OTSC clip for anal fistula closure. Colorectal Dis 14(9):1112–1117PubMed
Zurück zum Zitat Rayen J, Currie T, Gearry RB, Frizelle F, Eglinton T (2017) The long-term outcome of anti-TNF alpha therapy in perianal Crohn’s disease. Tech Coloproctol 21(2):119–124PubMed Rayen J, Currie T, Gearry RB, Frizelle F, Eglinton T (2017) The long-term outcome of anti-TNF alpha therapy in perianal Crohn’s disease. Tech Coloproctol 21(2):119–124PubMed
Zurück zum Zitat Resegotti A, Astegiano M, Farina EC, Ciccone G, Avagnina G, Giustetto A, Campra D, Fronda GR (2005) Side-to-side stapled anastomosis strongly reduces anastomotic leak rates in Crohn’s disease surgery. Dis Colon Rectum 48(3):464–468 Resegotti A, Astegiano M, Farina EC, Ciccone G, Avagnina G, Giustetto A, Campra D, Fronda GR (2005) Side-to-side stapled anastomosis strongly reduces anastomotic leak rates in Crohn’s disease surgery. Dis Colon Rectum 48(3):464–468
Zurück zum Zitat Ruffolo C, Penninckx F, Van Assche G, Vermeire S, Rutgeerts P, Coremans G, D’Hoore A (2009) Outcome of surgery for rectovaginal fistula due to Crohn’s disease. Br J Surg 96:1190–1195PubMed Ruffolo C, Penninckx F, Van Assche G, Vermeire S, Rutgeerts P, Coremans G, D’Hoore A (2009) Outcome of surgery for rectovaginal fistula due to Crohn’s disease. Br J Surg 96:1190–1195PubMed
Zurück zum Zitat Sandborn WJ, Fazio VW, Feagan BG, Hanauer SB, American Gastroenterological Association Clinical Practice Committee (2003) AGA technical review on perianal Crohn’s disease. Gastroenterol 125:1508–1530 Sandborn WJ, Fazio VW, Feagan BG, Hanauer SB, American Gastroenterological Association Clinical Practice Committee (2003) AGA technical review on perianal Crohn’s disease. Gastroenterol 125:1508–1530
Zurück zum Zitat Schloericke E, Hoffmann M, Zimmermann M, Kraus M, Bouchard R, Roblick UJ, Hildebrand P, Nolde J, Bruch HP, Limmer S (2012) Transperineal omentum flap for the anatomic reconstruction of the rectovaginal space in the therapy of rectovaginal fistulas. Colorectal Dis 14(5):604–610PubMed Schloericke E, Hoffmann M, Zimmermann M, Kraus M, Bouchard R, Roblick UJ, Hildebrand P, Nolde J, Bruch HP, Limmer S (2012) Transperineal omentum flap for the anatomic reconstruction of the rectovaginal space in the therapy of rectovaginal fistulas. Colorectal Dis 14(5):604–610PubMed
Zurück zum Zitat Schwandner O (2013) Video-assisted anal fistula treatment (VAAFT) combined with advancement flap repair in Crohn’s disease. Tech Coloproctol 17:221–225PubMed Schwandner O (2013) Video-assisted anal fistula treatment (VAAFT) combined with advancement flap repair in Crohn’s disease. Tech Coloproctol 17:221–225PubMed
Zurück zum Zitat Schwartz DA, Wiersema MJ, Dudiak KM, Fletcher JG, Clain JE, Tremaine WJ, Zinsmeister AR, Norton ID, Boardman LA, Devine RM, Wolff BG, Young-Fadok TM, Diehl NN, Pemberton JH, Sandborn WJ (2001) A comparison of endoscopic ultrasound, magnetic resonance imaging, and exam under anesthesia for evaluation of Crohn’s perianal fistulas. Gastroenterol 121:1064–1072 Schwartz DA, Wiersema MJ, Dudiak KM, Fletcher JG, Clain JE, Tremaine WJ, Zinsmeister AR, Norton ID, Boardman LA, Devine RM, Wolff BG, Young-Fadok TM, Diehl NN, Pemberton JH, Sandborn WJ (2001) A comparison of endoscopic ultrasound, magnetic resonance imaging, and exam under anesthesia for evaluation of Crohn’s perianal fistulas. Gastroenterol 121:1064–1072
Zurück zum Zitat Schwartz DA, Loftus EV Jr, Tremaine WJ et al (2002) The natural history of fistulizing Crohn’s disease in Olmsted County, Minnesota. Gastroenterol 122:875–880 Schwartz DA, Loftus EV Jr, Tremaine WJ et al (2002) The natural history of fistulizing Crohn’s disease in Olmsted County, Minnesota. Gastroenterol 122:875–880
Zurück zum Zitat Senéjoux A, Siproudhis L, Abramowitz L, Munoz-Bongrand N, Desseaux K, Bouguen G, Bourreille A, Dewit O, Stefanescu C, Vernier G, Louis E, Grimaud JC, Godart B, Savoye G, Hebuterne X, Bauer P, Nachury M, Laharie D, Chevret S, Bouhnik Y, Groupe d’Etude Thérapeutique des Affections Inflammatoires du tube Digestif [GETAID] (2016) Fistula plug in fistulising ano-perineal Crohn’s disease: a randomised controlled trial. J Crohns Colitis 10(2):141–148PubMed Senéjoux A, Siproudhis L, Abramowitz L, Munoz-Bongrand N, Desseaux K, Bouguen G, Bourreille A, Dewit O, Stefanescu C, Vernier G, Louis E, Grimaud JC, Godart B, Savoye G, Hebuterne X, Bauer P, Nachury M, Laharie D, Chevret S, Bouhnik Y, Groupe d’Etude Thérapeutique des Affections Inflammatoires du tube Digestif [GETAID] (2016) Fistula plug in fistulising ano-perineal Crohn’s disease: a randomised controlled trial. J Crohns Colitis 10(2):141–148PubMed
Zurück zum Zitat Soltani A, Kaiser AM (2010) Endorectal advancement flap for cryptoglandular or Crohn’s fistula-in-ano. Dis Colon Rectum 53(4):486–495PubMed Soltani A, Kaiser AM (2010) Endorectal advancement flap for cryptoglandular or Crohn’s fistula-in-ano. Dis Colon Rectum 53(4):486–495PubMed
Zurück zum Zitat Songne K, Scotte M, Lubrano J et al (2007) Treatment of anovaginal or rectovaginal fistulas with modified Martius graft. Colorectal Dis 9:653–656PubMed Songne K, Scotte M, Lubrano J et al (2007) Treatment of anovaginal or rectovaginal fistulas with modified Martius graft. Colorectal Dis 9:653–656PubMed
Zurück zum Zitat Tozer PJ, Burling D, Gupta A, Phillips RK, Hart AL (2011) Review article: medical, surgical and radiological management of perianal Crohn’s fistulas. Aliment Pharmacol Ther 33:5–22PubMed Tozer PJ, Burling D, Gupta A, Phillips RK, Hart AL (2011) Review article: medical, surgical and radiological management of perianal Crohn’s fistulas. Aliment Pharmacol Ther 33:5–22PubMed
Zurück zum Zitat Valente MA, Hull TL (2014) Contemporary surgical management of rectovaginal fistula in Crohn’s disease. World J Gastrointest Pathophysiol 5(4):487–495PubMedPubMedCentral Valente MA, Hull TL (2014) Contemporary surgical management of rectovaginal fistula in Crohn’s disease. World J Gastrointest Pathophysiol 5(4):487–495PubMedPubMedCentral
Zurück zum Zitat Van Koperen PJ, D’Hoore A, Wolthuis AM, Bemelman WA, Slors JF (2007) Anal fistula plug for closure of difficult anorectal fistula: a prospective study. Dis Colon Rectum 50:2168–2172PubMed Van Koperen PJ, D’Hoore A, Wolthuis AM, Bemelman WA, Slors JF (2007) Anal fistula plug for closure of difficult anorectal fistula: a prospective study. Dis Colon Rectum 50:2168–2172PubMed
Zurück zum Zitat Vollebregt PF, van Bodegraven AA, Markus-de Kwaadsteniet TML, van der Horst D, Felt-Bersma RJF (2018) Impacts of perianal disease and faecal incontinence on quality of life and employment in 1092 patients with inflammatory bowel disease. Aliment Pharmacol Ther 47(9):1253–1260PubMedPubMedCentral Vollebregt PF, van Bodegraven AA, Markus-de Kwaadsteniet TML, van der Horst D, Felt-Bersma RJF (2018) Impacts of perianal disease and faecal incontinence on quality of life and employment in 1092 patients with inflammatory bowel disease. Aliment Pharmacol Ther 47(9):1253–1260PubMedPubMedCentral
Zurück zum Zitat Wilhelm A (2011) A new technique for sphincter-preserving anal fistula repair using a novel radial emitting laser probe. Tech Coloproctol 15:445–449PubMed Wilhelm A (2011) A new technique for sphincter-preserving anal fistula repair using a novel radial emitting laser probe. Tech Coloproctol 15:445–449PubMed
Zurück zum Zitat Wilhelm A, Fiebig A, Krawczak M (2017) Five years of experience with the FiLaC™ laser for fistula-in-ano management: long-term follow-up from a single institution. Tech Coloproctol 21:269–276PubMedPubMedCentral Wilhelm A, Fiebig A, Krawczak M (2017) Five years of experience with the FiLaC™ laser for fistula-in-ano management: long-term follow-up from a single institution. Tech Coloproctol 21:269–276PubMedPubMedCentral
Zurück zum Zitat Zmora O, Tulchinsky H, Gur E, Goldman G, Klausner JM, Rabau M (2006) Gracilis muscle transposition for fistulas between the rectum and urethra or vagina. Dis Colon Rectum 49:1316–1321PubMed Zmora O, Tulchinsky H, Gur E, Goldman G, Klausner JM, Rabau M (2006) Gracilis muscle transposition for fistulas between the rectum and urethra or vagina. Dis Colon Rectum 49:1316–1321PubMed
Metadaten
Titel
Chirurgische Therapie von Fisteln
verfasst von
Christoph Holmer
Martin E. Kreis
Copyright-Jahr
2020
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-59104-8_19

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Erhebliches Risiko für Kehlkopfkrebs bei mäßiger Dysplasie

29.05.2024 Larynxkarzinom Nachrichten

Fast ein Viertel der Personen mit mäßig dysplastischen Stimmlippenläsionen entwickelt einen Kehlkopftumor. Solche Personen benötigen daher eine besonders enge ärztliche Überwachung.

Nach Herzinfarkt mit Typ-1-Diabetes schlechtere Karten als mit Typ 2?

29.05.2024 Herzinfarkt Nachrichten

Bei Menschen mit Typ-2-Diabetes sind die Chancen, einen Myokardinfarkt zu überleben, in den letzten 15 Jahren deutlich gestiegen – nicht jedoch bei Betroffenen mit Typ 1.

15% bedauern gewählte Blasenkrebs-Therapie

29.05.2024 Urothelkarzinom Nachrichten

Ob Patienten und Patientinnen mit neu diagnostiziertem Blasenkrebs ein Jahr später Bedauern über die Therapieentscheidung empfinden, wird einer Studie aus England zufolge von der Radikalität und dem Erfolg des Eingriffs beeinflusst.

Costims – das nächste heiße Ding in der Krebstherapie?

28.05.2024 Onkologische Immuntherapie Nachrichten

„Kalte“ Tumoren werden heiß – CD28-kostimulatorische Antikörper sollen dies ermöglichen. Am besten könnten diese in Kombination mit BiTEs und Checkpointhemmern wirken. Erste klinische Studien laufen bereits.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.